Preheat oven to 350 degrees. Grease 13- by 9-inch baking pan.
Cook pasta according to package directions. Drain and reserve.
To prepare sauce: Combine cream and milk and heat (in microwave).
In saucepan, melt 4 Tbsp butter. Wisk in flour and cook for 1 minute. Gradually add hot milk and cream until smooth sauce forms, stirring constantly. Bring sauce to boil and remove from heat. Slowly stir in cheeses until melted.
Combine cream sauce a little at a time with pasta. Season pasta mixture with salt and pepper to taste. Sprinkle top with bread crumbs and remaining Parmesan cheese. Dot with remaining butter.
Bake in preheated oven for about 30 minutes, or until brown and bubbly.